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It presents with a broad clinical spectrum, ranging from asymptomatic or non-specific symptoms, such as fatigue or lightheadedness, to severe manifestations, including nausea, vomiting, alteration of consciousness, and even coma, which can be life-threatening 3,4

the patients in these studies had reported efficacy rates of 50 to 100%, but they also had recurrence rates of 9 to 50%

doi: 10.3390/antiox11051034 Summary Keywords osteoarthritis, ferroptosis, metabolic reprogramming, immunometabolic crosstalk, iron homeostasis, lipid peroxidation, inflammatory microenvironment Citation Xia S, Li L, Shi Z, Sun N and He Y (2025) Ferroptosis in osteoarthritis: metabolic reprogramming, immunometabolic crosstalk, and targeted intervention strategies

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Indeed, the link between ROS and TGF-1-induced epithelial-mesenchymal transition (EMT) has been demonstrated in endometrial cell pathology 139