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Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity

Chemical Information CAS Number 137525-51-0 Secondary CAS 1356647-49-2 Purity 99%+ HPLC Verified Molecular Formula C 62 H 98 N 16 O 22 Molar Mass 1419.5347 g/mol Form Factor Lyophilized Powder Synonyms Research Applications Gastroenterology Research: BPC-157 is investigated in preclinical gastrointestinal models for its potential influence on mucosal cytoprotection, gastric lesion repair, NSAID-associated tissue injury, and intestinal barrier function

After controlling for many factors that are known to influence risk of cancer, the researchers reported a 30% increase in lung cancer risk associated with the use of vitamin B12 (taken as an individual vitamin) and a 40% increase in risk for those who took B6

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Although low serum B12 levels have been associated with increased bone turnover and fracture risk (9) , long-term B12 and folic acid supplementation did not improve bone mineral density (38) , or reduce osteoporotic fracture incidence in elderly individuals with elevated plasma homocysteine levels (39)