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Pigmented Lesions of the Oral Mucosa Pocket Dentistry Figure 2 from Smokers' melanosis in a Nigerian population “Melanosis” in the small and large intestine Melanosis coli is dark brown black pigmentation of colorectal mucosa associated with chronic use of laxatives containing anthraquinone. Examples of such laxatives include senna and rhubarb derivatives. Clinical Importance: There is no association Melanosis coli Wikipedia
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