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Acute systemic LPS injections induce pronounced but reversible changes in astrocyte gene expression in the prefrontal cortex, along with an approximate 25% decrease in astrocyte branch and process volumes, but with few currently detectable changes in astrocyte physiology and basic preservation of astrocyte core homoeostatic functions such a potassium buffering

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In this study, no difference in enzyme activity in TEC or control red cells was noted, thus suggesting there is minimal loss of enzyme activity beyond the first days of red cell life ( 37 )