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But until then, what has occurred is only synaptic damage, small lesions that do not kill the neurons but do cause problems

Lipton RB, Stewart WF, Ryan RE Jr, et al

10.1073/pnas.95.12.6705 Dawson PE, Muir TW, Clark-Lewis I, Kent SB: Synthesis of proteins by native chemical ligation

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Together, these help show the value of any specific therapeutic strategies and drugs when attempting to ameliorate disease severity