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To evaluate the physiological relevance of these new spines and to determine the neurotransmitter signature of resident synapses, HGF treatment- induced spines labeled with mRFP-p-actin were immunostained for the universal presynaptic marker Synapsin that is located in the presynaptic active zones and the excitatory presynaptic marker VGLUTl that is found at glutamatergic presynaptic synapses

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The authors research group recently revealed that the mRNA expressions of the MT-IA and MT-IG genes were significantly inversely with the PU.1 gene correlated in 43 primary acute AML specimens (MT-IG: R = 0.50, p 20% of lymphoma cells was associated with a significantly (p = 0.004) poorer 5-year survival, independent of age, stage or international prognostic index [27]

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