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Acta Neurol Taiwan 14:4854 Alvarez M, Prieto AE, Portilla N, Moya D, Rincon O, Guzman I (2025) Metformin-induced vitamin B12 deficiency: An underdiagnosed cause of diabetic neuropathy

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Additionally, SAM plays a pivotal role as the primary provider of methyl groups, which are crucial for various processes, including gene regulation

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Significant recovery was observed in the nasal group compared to the oral group at POD 16 (p = 0.005) and POD 24 (p = 0.003)." Conclusion Intra-nasal vitamin B12 sprays were found to be conducive adjuvants to treat transient neurosensory disturbances following third molar surgery