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See Example Case 3 In case 3, an individual with documented vitamin B12 deficiency the neurotransmitter findings were: Epinephrine 4.2 g/go cretonne (8-12) Norepinephrine 26.6 g/grocer (30-55) Dopamine 89.2 g/grocer (125-175) Serotonin 48.6 g/grocer (175-225) GABA 7.0 mol/grocer (2.0-4.0) Glutamate 45.3 mol/grocer (10-25) PEA 529.70 nmol/grocer (175-350) Histamine 82.7 g/grocer (10-22) Cretonne 35.0 mg/do Glutathione in RBC 38 mol/L (200-400) The results show that the individual is low in epinephrine, norepinephrine, dopamine and serotonin, all related to diminished methionine cycle function and decreased methylation

Frontiers in Medicine (Lausanne), 9 , 911861

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[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Leal-Ugarte E., Peralta V., Meza-Espinoza J.P., Duran J., Macias-Gomez N., Bocanegra-Alonso A., Lara-Ramos J

RESULTS Developmental stage and sex modulate the cellular transcriptional state in the developing lung To gain a comprehensive understanding of the sex specific transcriptional changes in the neonatal lung at PND 1 (saccular stage of lung development), PND 7 (early alveolar stage of lung development) and PND 21 (late alveolar stage of lung development), we collected lungs from male and female neonatal mice under room air conditions and processed them for single cell RNA sequencing ( Figure 1A )