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Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2

Research progress on pathogenesis of chronic fatigue syndrome and treatment of traditional Chinese and Western medicine

M1 macrophages are characterized by high inducible nitric oxide synthase (iNOS) expression and the secretion of pro-inflammatory factors, whereas M2 macrophages express molecules such as arginase-1 (Arg1) and interleukin-10 (IL-10) and participate in tissue repair ( in vivo do not exist as fixed binary states, but rather display a continuum of functions shaped jointly by microenvironmental signals, metabolic reprogramming, and epigenetic regulation ( In recent years, studies of immunometabolism have gradually revealed the important role of metabolic reprogramming in regulating immune cell function

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MATERIALS AND METHODS General procedures The published protocols (1) were followed, with exceptions noted below