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Novel treatment of chronic graft-versus-host disease in mice using the ER stress reducer 4-phenylbutyric acid

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doi: 10.1016/j.drudis.2015.01.009

Multiple elements of cellular response pathways, such as receptors, adaptors, signal transducers, or transcription factors, are modified and controlled by the ubiquitination system, which thus manages stresses, repairs damages, and restores homeostasis

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