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16 Sorafenib-induced ferroptosis promotes the antitumor mechanism of sorafenib, and ncRNAs have been shown to mediate HCC cell ferroptosis

Uncontrolled Hypertension IV infusions can lead to increased blood volume and pressure, complicating hypertension management

Nevertheless, research on CPT activation or inhibition highlights the pharmacological modulation of CPT-dependent FAO, especially on different CPT isoforms, as a promising anti-inflammatory/antitumor therapeutic strategy for numerous disorders

We also discuss the potential targets of ferroptosis in the treatment of cardiovascular disease and describe the current limitations and future directions of these novel treatment targets

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