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Description

Beta4 integrin activates a Shp2Src signaling pathway that sustains HGF-induced anchorage-independent growth

The goal of MEK inhibitors is to block MEK signaling and therefore block the pathway

Proc Natl Acad Sci U S A [Internet]

Confronted with the substantial global increase in PD prevalence and the persisting unmet clinical needs in managing both motor and non-motor symptoms, the development of multi-target therapeutic strategies is critically important