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In a large longitudinal study of 1441 people with type 1 diabetes (T1D) in the Diabetes Control and Complications trial (DCCT), intensive insulin treatment reduced the risk of developing DPN by 60%, but a multifactorial approach, including managing hypertension, obesity, and hypertriglyceridemia, is necessary for those with type 2 diabetes (T2D) because of the diseases heterogeneous nature [41]

The results of that study were used to design a slightly different vitamin/mineral formulation, which was used in a randomized 12-month study in combination with 5 other nutritional/dietary treatments [23], referred to in this paper as Adams 2018

For Other Issues: Other issues will be detected via blood tests and tested by doctors who will decide the right dosage to address the needs of your body and specific issues