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Tregs take up lactate via MCT1 (encoded by Slc16a1), convert it to pyruvate for entry into the TCA, and generate phosphoenolpyruvate (PEP) via PEP carboxykinase (PEPCK), which feeds back to promote gluconeogenesis and nucleotide synthesis to support Treg proliferation

Inokoshi Y, Tanino Y, Wang X, Sato S, Fukuhara N, Nikaido T, et al

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J Food Prot 86:100184 [DOI] [PubMed] [Google Scholar] Palaniswamy R, Veluchamy C (2017) Biosorption of heavy metals by spirulina platensis from electroplating industrial effluent

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