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The method of claim 28, wherein the disease is selected from the group consisting of: Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, other dementias and neurodegenerative diseases, spinal cord injury, traumatic brain injury, sensorineural hearing and vision loss

Indeed translocation of mTORC1 from the cytoplasm to the lysosome, a rich compartment in amino acids, is critical for mTORC1 activation ( per se is also able to regulate mTORC1 activity ( In brief, activation of the GCN2-ATF4 amino acid stress pathway and inhibition of protein synthesis through inhibition of mTORC1 demonstrates the strong proteogenic role played by cysteine in tumor cells

This reinforces the significant impact of trastuzumab on improving breast cancer survival in real-world clinical settings

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No mandatory waiting period between them is needed