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HTLV-1 is the etiological agent of the adult T-cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic progressive disabling disease characterized by demyelination, axonal loss, neuronal degeneration, and gliosis

Its primary domain is inside the mitochondria, the microscopic powerhouses responsible for generating adenosine triphosphate (ATP), which is the energy currency of the cell

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