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Patients with genetic forms of cerebral folate deficiency typically present with developmental delay and regression, intractable seizures, abnormal movements (ataxia and dyskinesia), and delayed myelination (31

In: Mattila-Sandholm T, Saarela M, editors

Fundam Clin Pharmacol 23:8995

"AS2 Protocol"

Quick Answer: For most patients, metformin timing does not need adjustment specifically for exercisemaintain your prescribed schedule with meals for optimal tolerance and effectiveness