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While these drugs are effective, long-term use in aging individuals, whose metabolic function is usually compromised, can lead to drug dependency and resistance (19)

Semaglutide is FDA-approved

Antibodies and reagents Antibodies and reagents for all experiments are listed in Supplementary Table 3

Six type of tissue samples were obtained from each calf: ileum, distal jejunum, ileocaecal valve, ileal lymph nodes, distal jejunal lymph nodes, and ileocaecal valve lymph nodes