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However, more complex therapies or larger volumes of fluid may extend the duration of the session, sometimes up to a few hours

This vulnerability is further complicated by the blood-brain barrier (BBB), which tightly regulates iron influx and efflux, creating distinct compartmentalization of iron metabolism [10]

It does not establish reduced-versus-oxidised content, endotoxin, sterility, particulates, concentration accuracy or suitability for injection

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Genet 19 , 31793189 (2010)