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The copper component creates mild irritation that typically subsides within minutes

Consistent results have been reported in other studies, where SIN suppressed NF-B activation and reduced the release of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6 (108)

: SIRPalpha(+) dendritic cells promote the development of fibroblastic reticular cells in murine peripheral lymph nodes

Male SD rats (150 20 g) were obtained from the Laboratory Animal Center of Southwest Medical University (Luzhou, China) and maintained under standard laboratory conditions according to the guidelines

Multiple delivery routes including oral, transdermal, vaginal, ocular, and nasal have been explored to optimize the therapeutic use of chitosan NPs