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Les ions cuivre(II) sont essentiels l'activit de la lysyl oxydase, l'enzyme qui catalyse la rticulation covalente des fibres de collagne et d'lastine

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Both long-term heavy drinking and occasional heavy drinking can, to varying degrees, decrease HDL-C, increase plasma viscosity and fibrinogen concentration, cause platelet aggregation, impair endothelial function, increase inflammatory responses, increase heart rate, and inhibit cardiac contractile function, thereby increasing the incidence of CVD, morbidity and mortality (50, 51)

In light of this evidence, early diagnosis of gestational diabetes mellitus (GDM) is crucial, as it predisposes offspring to the early development of type 2 diabetes and cardiovascular diseases and allows for the timely improvement and optimization of clinical management and therapeutic interventions [31,32,33,34]