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Importantly, mTORC1 is also involved in the regulation of mitochondrial metabolism and mitochondrial functions

Using non-targeted metabolomics and RNA sequencing, this study investigates the mechanisms underlying hypertension-induced ED

It is initiated by changes in intracellular and extracellular lipid peroxidation levels, the balance in GSH oxidation and reduction, and intracellular iron metabolism abnormalities, which promote CNS damage and neuronal death [130]