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Comparing B use as a group against alternative hypertensive drug classes in the wider hypertension population, we did not find any significant difference in terms of either Alzheimer's risk or risk of any dementia (Supplementary Table 4)

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However, in people with T2D and MASLD, 24 weeks of efinopegdutide 10 mg reduced liver fat content by 72.7% compared to 42.3% reduction with semaglutide 1 mg despite similar WL achieved with both interventions [79]