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64,555 ERAD/UPR and autophagy: managing endoplasmic reticulum stress The ER is a critical site for protein folding and quality control

Curcumin neither inhibits the transcription of p53 mRNA nor protects tumor cells against the cytotoxic effect of cisplatin on HepG2 cells [126]

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In addition, there is an increase in the expression of IL-6, TNF-, and increased oxidative damage coupled with a reduction in antioxidant capacity (Guest et al., 2014