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Previous studies (Bussow et al., 2005

Crit Rev Oncog

This process is initiated by the transport of pyruvate, the final product of the glycolysis pathway, from the cytosol to the mitochondrial matrix

[148] [157] In addition, clomipramine has high toxicity in overdose and can potentially result in death, whereas death rarely, if ever, occurs with overdose of SSRIs