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In this study, GSA is used to examine which of the processes captured in the model for the GSH system are the most important in a control mouse retina compared to degenerative retina with RP

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Therefore, the modified Fx polypeptides provided herein contain at least one amino acid modification, such as at least the substitution of an amino acid, which is a substitution with N, Q, S, T, W, C, or And in a position corresponding to position 196 with reference to the amino acid sequence shown in SEQ ID NO: 134

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Compounding these pharmacological issues is the lack of reliable biomarkers for monitoring ferroptosis in the human brain