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In casecontrol study, diabetic patients with peripheral neuropathy had lower serum zinc levels, and zinc levels were negatively correlated with HbA1c, neuropathy scores (NSC and MNSI), and nerve conduction [590]

Hellmich, H

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Certain antihistamines notably cimetidine and promethazine have been shown to actually reduce DAO activity with prolonged use, potentially worsening the underlying deficiency over time