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The peroxidase mimetic activity exhibited by nanozymes could be catalyzed by following two steps: All of the studies reporting intrinsic peroxidase-like activity of iron oxide nanoparticles have shown that acidic pH (pH 4.0) is one of the fundamental requirements driving the oxidation of peroxidase substrates (TMB, OPD, ABTS), which finally results in corresponding colorimetric product formation used in the detection of a variety of analytes

VLA15 is expected to disable the outer surface protein A (OspA) of the Borrelia burgdorferi bacteria within the tick gut prior to transmission to humans