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Activation of hepatic stellate cells (HSCs) that transdifferentiate from vitamin Astoring pericyte-like cells to -SMA-positive, collagen-producing myofibroblasts is now well-established as the central driver of fibrosis (76, 77)

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This further supports the notion of a differential, complementary and coherent metabolic phenotypic differentiation between astrocytes and neurons with regards to neuroenergetics

34 LuJ.HolmgrenA

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