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Additionally, the oxidative stress response system governed by Nrf2 is likely impaired due to cellular oxidative damage, as previous articles reported that Nrf2 is inactivated in chronically damaged kidneys [73]

Altuntas I, Aksoy H, Coskun I, Caykyl A, Akcaay F

eds) (McGraw-Hill) (1996 )

intestinalis -derived butyrate correlates with improved anti-PD-1 responses by increasing intratumoral CD8 + T cell infiltration (148)

As shown by research, GlyNAC supplementation can improve glutathione deficiency, which is crucial in reducing oxidative stressa factor linked to age-associated defects in older humans