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Biochem Biophys Res Commun (2013) 436:58590

Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein

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Biomarkers can be used as CSF or imaging depending on cost, availability, and patient preference, in particularly difficult cases where the diagnosis is ambiguous and both patient and clinician want to determine the etiology of cognitive impairment to modify the plan of care (counseling and prescription of cholinesterase inhibitors and/or memantine).To better understand the complexities of this diverse illness and increase diagnostic precision, the study suggests investigating new biomarkers outside of the amyloid and tau pathology [152]