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This isnt just in your head

Activation of the CB1 promotes the expression of lipogenic genes that are crucial for de novo fatty acid synthesis, increases oxidative stress, reduces antioxidant activity, and enhances fibrosis in the liver (15, 16)

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MASLD is now the leading cause of cirrhosis in the U.S., surpassing hepatitis C and alcohol overuse

Therefore, we transfected TRPM7 siRNA and TRPM7 (ion channel segment) overexpression plasmid into N2a cells to explore the relationship between TRPM7 and pyroptosis