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Description

Cagrilintide is a synthetic 37-amino-acid acylated analog of the pancreatic hormone amylin, built on a pramlintide-like backbone with amino-acid substitutions and an N-terminal fatty-diacid (C20) modification via a gamma-glutamic acid linker

Employing a liquid chromatography mass spectrometry (LCMS) protocol hereafter referred to as the HILIC method (hydrophilic interaction liquid chromatography), we quantified 1,064 metabolites in positive ion-mode and 616 in negative ion-mode