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Central administration of NPY in the brain via intracerebroventricular (i.c.v.) injections has been shown to exert antidepressant-like effects in forced swim test (FST) studies

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The results demonstrated statistically significant improvements in higher-order cognitive processes, specifically memory consolidation, verbal learning, and the speed of visual information processing

In another study, phosgene-exposed animals (500 ppm for 1 minute) received saline (positive control), a low (50 mg/kg), moderate (100 mg/kg), or high (200 mg/kg) dose of NAC, or were exposed to phosgene and untreated (control) (Ji et al., 2010)