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J Nutr 137 : 216S222S

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156 Hepatic ischemia/reperfusion injury mice induce a depression-like phenotype via the subdiaphragmatic vagus nerve-mediated gutmicrobiotaliverbrain axis, manifested as splenomegaly, systemic inflammation, reduced synaptic protein expression in the prefrontal cortex, abnormal gut flora composition, and altered blood metabolites and lipids