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Discussion There is a strong regulatory need for sensitive mutagenicity evaluation of NAs, including NDSRIs, for both approval of new medicines and for assessing safety risks in already approved products

For instance, Xu et al

Desai P

doi: 10.1080/20013078.2018.1470442 221 LembergKMGoriSSTsukamotoTRaisRSlusherBS

By identifying the relative contributions of genes and the environment to anti-oxidant variation between individuals, new therapeutic strategies can be developed