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Reduced or conjugated curcumin forms, such as 4HC, 6HC, and curcumin sulfate, showed a diminished ability to inhibit cyclooxygenase-2 (COX-2) synthesis (108)

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Of note, limb acupoints including ST36, Shangjuxu (ST37), and Xiajuxu (ST39), were more commonly used in POI patients [108]

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Thin films or coatings of such nanopowder functional materials provide sustainable and promising approaches for fabricating devices for real practical applications 19,20,21