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Description

As phase II enzymes, GSTs detoxify chemical compounds through catalyzing nucleophilic attack by the thiol group in reduced glutathione (GSH) on a wide range of electrophilic substrates [37, 40, 41]

Some research also explores acetate or trifluoroacetate (TFA) salt forms

Younger J, Parkitny L, McLain D

Acta 1831 (2013) 523532

The peak response potentiation induced by EAR-20 was intermediate between GluN2A and GluN2B conditions recorded previously in HEK293 cells (54.26% 8.15% for native NMDARs versus 15.68% 6.19% for GluN2A-containing heterologous NMDARs or 102.6% 24.02% for GluN2B-containing heterologous NMDARs)