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More specifically, NRF2 and KEAP1 have been analyzed in postmortem motor cortex and spinal cord specimens from ALS patients and a reduction in both NFE2L2 mRNA and NRF2 protein has been found in ALS patient tissues when compared to control ones

Somatostatin receptors in human cancer: incidence, characteristics, functional correlates and clinical implications

Zach Whitfield was one of them

38,39,40,41 Simultaneously, this metabolic alteration benefits T eff cells by reducing their reliance on oxygen for energy production, which enables them to maintain cytokine production and cytolytic activity even when they migrate into microenvironments within solid tumors that have low oxygen levels

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