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Rights and permissions About this article Cite this article Sadiq, S., Khwaja, S

We hypothesize that inhibiting intracellular glutamine transport via ASCT2, such as with V-9302, may be a more effective strategy for targeting glutamine metabolism in PIK3CA -mutant cancer cells than targeting downstream enzymatic activities, such as GLS1 or glutamine synthetase

Understanding these patterns helps create better support strategies

Statistics All values are presented as means SE

In some cases, further work needs to happen to find and address the root cause(s) that are contributing to the condition, such as infections , traumatic stress, and toxins