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By contrast, M2 macrophages are involved in Th2-dependent immune cascades and play an anti-inflammatory role

doi: 4 10.3945/an.3115.010785

Molecular analysis has confirmed that activation of the Ang-Tie pathway as a result of the connection between Ang-1 and Tie2 receptor on the M2 subpopulation of monocytes, hematopoietic stem cells (HSCs), and endothelial cells (ECs) of blood and lymphatic vessels elicits maturation or stabilization of blood vessels [80]

Latham et al., 2024)

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