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Gumen AV, Kozinets IA, Shanin SN, Malinin VV, Rybakina EG

doi: 10.1016/j.rvsc.2014.07.008

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Atherosclerosis progression, as a chronic inflammatory mechanism, is characterized by immune system dysregulation associated with increased pro-inflammatory cytokine production, including interleukin 6 (IL-6), tumor necrosis factor- (TNF-), and IL-1, as well as pattern recognition receptor proteins like CRP (170, 261267)