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doi:10.1016/j.numecd.2022.05.008 Jerneren F, Cederholm T, Refsum H, et al

Myeloid cells, including macrophages and neutrophils, are especially implicated in the respiratory burst

Various factors, including genetic predisposition, immune dysregulation, and alterations in the gut microbiota, are believed to contribute to the pathogenesis of UC

Several types of medicines are often used to manage IBD, including aminosalicylates, steroids, immunosuppressants and biologics

To construct the modified homozygous strain expressing GAP1 as the counter-selectable marker in the BY4743 background, the KanMX fragment was amplified from pFA6A-KanMX6 [32], and HS fragments for pGAP1 were amplified from yeast genomic DNA and these fragments plus pGSH1 (above) assembled into pRS315 to give pRS315- HS-KanMX-pGSH1-HS