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The depigmenting activity is carried out by specific active ingredients, assisted by a superficial peeling action that promotes epidermal renewal and permits the delivery to deeper dermal layers: it includes antioxidants and dermo-normalising agents (like glutathione and hyaluronic acid), salicylic acid to increase cell turnover, melanin formation and transport blockers and melanogenic enzyme blockers, including tranexamic acid

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147 When the intracytoplasmic Ca 2+ concentration increases, it can activate calcium-dependent proteases and the opening of transition pores, then affect mitochondrial permeability and result in the loss of mitochondrial membrane potential

TABLE 3 Water activity and moisture content of black peppercorn

Our hydration and recovery drips quickly replenish lost fluids and electrolytes, helping muscles recover faster and reducing fatigue