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Thyroid 30(5):704-712, 2020

Genomic and functional characterization of the oas gene family encoding O -acetylserine (thiol) lyases, enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana

doi: 10.3389/fimmu.2022.969509 73 Johnson-HuangLMSurez-FariasMPiersonKCFuentes-DuculanJCuetoILentiniTet al

Downregulated low-density lipoprotein receptor (LDLr) gene, increased liver enzymes [alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH)], cholesterol, triglycerides (TG), low-density lipoprotein (LDL), glucose, and total bilirubin

The pharmacometabolomic approach provided verification of target engagement when using combined treatment with probenecid and NAC in children with severe TBI