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Description

Future translational efforts should pursue several directions: first, conducting deep-phenotyping trials in biopsy-confirmed MASH patients, using positron emission tomography to quantify hepatic glucose uptake and correlating these findings with intrahepatic insulin signaling (e.g., p-AKT)

Ufnal M, Nowiski A

Jan 1 2018;187(1):60-74

Metabolic decompensation: usually occurs in infants aged 3 to 24 months, manifested by hypoglycemic coma, feeding difficulties, irritability, lethargy, hepatomegaly, elevated liver enzymes, and elevated transaminases