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JS continued to experience seizures, which later evolved into predominantly nocturnal events characterized by leftward eye deviation, gasping sounds, facial twitching, limb stiffening, and postictal aphasia

Tregs are responsible for maintaining immune homeostasis by suppressing overactive immune responses, preventing autoimmune reactions, and ensuring tolerance to self-antigens [321]

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Characterized by abundant regulatory T cells (Tregs), myeloid-derived suppressor cells (MDSCs), and M2-polarized tumor-associated macrophages (TAMs), all of which inhibit antigen presentation and effector T-cell function