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Wild-type TP53 hampers the shunt of the glucose carbon to anabolic pathways by binding to and inhibiting the G6PD, whereas mutant TP53 is unable to affect the G6PD activity (175)

The protein expression levels of ischemic and non-ischemic gastrocnemius muscle tissues at different time points (the 2nd, 5th, 7th, and 14th day post-HLI) were determined by western blot analysis (Fig