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Bortezomib-induced aerobic glycolysis contributes to chemotherapy-induced painful peripheral neuropathy

American Heart Association

The sulfur-containing amino acids methionine and cysteine, N -acetylcysteine, an acetylated analogue of cysteine, the methionine metabolite S -adenosylmethionine, -lipoic acid, and the tripeptide glutathione (GSH) all contribute to the chelation and excretion of metals from the human body

doi: 10.1038/s41598-021-98317-w 161 MagyariM

41 A phase I study evaluates the most promising agent, QR-010 (ProQR Therapeutics, Leiden, The Netherlands), which is intranasally applied to CF patients that are either homozygous for the F508del mutation or compound heterozygous (NCT02532764)