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For instance, Pt@PCN222-Mn nanozymes demonstrated superior efficacy in attenuating dextran sodium sulfate (DSS)-induced colitis in mice compared to the equivalent dose (0.5 mg/kg) of the small-molecule drug 5-ASA [96]

A report demonstrated that in 69 mtDNA variants, the rs28357671 locus of the MT-ND6 gene was significantly associated with mitochondrial function genes in allergic diseases, including: NLR Family Member X1 (NLRX1), oculocutaneous albinism II (OCA2) and coiled-coil-helix-coiled-coil-helix domain containing 3 (CHCHD3)